A group of people walk together outdoors representing connection independence and quality of life while living with neuroimmunologic conditions.

Neuroimmunology

Expert care for autoimmune brain and spine conditions

Neurological conditions that involve the immune system can be complex and life-changing. The neuroimmunology specialists at UTMB Health care for patients with disorders in which the immune system mistakenly attacks the brain, spinal cord, or nerves—causing problems with vision, movement, memory, or sensation.

Our experts understand the challenges of living with conditions such as multiple sclerosis, neuromyelitis optica, and autoimmune encephalitis. Using advanced diagnostic tools, infusion therapies, and disease-modifying treatments, the team works to control inflammation, prevent relapses, and protect long-term function. Each care plan is personalized to help you manage symptoms, maintain independence, and enhance quality of life.

A neurologist reviews brain imaging with a patient during an immunotherapy consultation for neuroimmunologic disorders.

  Conditions We Treat

A patient receives infusion therapy while a nurse provides support during immunotherapy treatment for neurologic conditions.

  Services & Procedures

We've highlighted some of the most common services—please explore the conditions list for treatments by condition.

Can’t find what you're looking for? Contact the care team at the clinic for assistance.

  Your Care Team Each provider may treat different conditions. Click on a profile to see their areas of specialty.

 Frequently Asked Questions.

Two adults laugh together outdoors representing connection emotional wellbeing and quality of life while living with neuroimmunologic conditions.

  Our Locations

image of female UTMB Health patient wearing all black and standing by "Greetings from Kemah" sign

Deep Brain Stimulation changes life for woman with tremors

Reba Smith-Weeden’s hand shook so bad, she couldn’t drink a cup of coffee. She has a condition called essential tremor that prevented her from carving the Thanksgiving turkey one year at her Kemah home.

“I couldn’t do it,” she said.

Essential tremor is a neurological condition that is 10 times more frequent than Parkinson’s disease. It is an involuntary tremor that can happen as someone tries to do an everyday, normal movement, such as trying to pick up and hold a cup of coffee.

Smith-Weeden, 67, first noticed some shaking when she was in her 40s. At the time, she attributed it to being hungry or anxious. It got worse over 25 years. For the last four years, the shaking has been a major issue in her life.

“It was just a little bit of shaking in the beginning, but it slowly got worse,” Smith said. “I couldn’t do normal things.” close-up shot of female UTMB Health patient using tools including scissors and fine wire to make jewelry

She couldn’t write her own name with her dominant hand. She learned to write it with her left, even though she still struggled with the shaking as she did it.

She used to make jewelry out of pieces of sea glass she collected in Mexico. She would wrap and weave wire around the sea glass to create jewelry. “I haven’t been able to do that,” she said.

Smith-Weeden started seeing a neurologist and tried a number of different medications. “Nothing seemed to work,” she said. “I was still shaking.”

A solution

Her doctor suggested she consider deep brain stimulation, often abbreviated DBS, a two-part operation that allows electrical stimulation to the brain.

Curious, Smith-Weeden began her research. She found a video online of a man who had the same type of surgery.

“He was still on the table, and they gave him a violin and he could play,” she said. “I was just like, wow! He wasn’t shaking. And he played it beautifully.”

A small mechanism turned the electrical stimulation on. She was convinced.

She met Dr. Patrick Karas, a neurosurgeon, who had just joined UTMB and performed deep brain stimulation.

“He made me feel at ease,” Smith-Weeden said. “He has a good bedside manner.”

The deep brain stimulation procedure involved two operations. The first surgery implants the electrodes in the brain. The second operation connects the electrodes to a pacemaker-type device in the chest.

Smith-Weeden had her first surgery in January and the second in February. Karas told her the device would be turned on one month after the initial surgery, but the shaking would stop immediately when the device is turned on.

The outcome

She remembers the day the shaking stopped. She had a follow-up appointment to test the device and how it was signaling her brain. The staff turned on the neurotransmitter.

Then her head stopped shaking and her voice tremors disappeared.

“They noticed it first before I did,” Smith-Weeden said. “I just cried. They programmed my neurotransmitter to tell my brain to stop shaking.”

They asked her to draw a spiral, and she did. She tried signing her name, and she could.

Now, she can put on her make-up. She can handcraft jewelry again. And she smiles a lot.

“I can drink my coffee without spilling it, I can eat without shaking, and I can brush my teeth.” Smith-Weeden said.

“This is life changing.”